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POCUS: mining genomic sequence annotation to predict disease genes

Here we present POCUS (prioritization of candidate genes using statistics), a novel computational approach to prioritize candidate disease genes that is based on over-representation of functional annotation between loci for the same disease. We show that POCUS can provide high (up to 81-fold) enrich...

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Detalhes bibliográficos
Main Authors: Turner, Frances S, Clutterbuck, Daniel R, Semple, Colin AM
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC329128/
https://ncbi.nlm.nih.gov/pubmed/14611661
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