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Assembly of the SMRT–histone deacetylase 3 repression complex requires the TCP-1 ring complex
The acetylation of histone tails is a primary determinant of gene activity. Histone deacetylase 3 (HDAC3) requires the nuclear receptor corepressor SMRT for HDAC enzyme activity. Here we report that HDAC3 interacts with SMRT only after priming by cellular chaperones including the TCP-1 ring complex...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Cold Spring Harbor Laboratory Press
2002
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC187500/ https://ncbi.nlm.nih.gov/pubmed/12502735 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1037502 |
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