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Ski is involved in transcriptional regulation by the repressor and full-length forms of Gli3
Transcription factor Glioblastoma-3 (Gli3) is cleaved in the anterior region of the limb bud to generate its repressor form. In contrast, Sonic hedgehog (Shh) signaling from the posterior zone of polarizing activity blocks Gli3 processing and then induces the expression of Gli3 target genes, includi...
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| Main Authors: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cold Spring Harbor Laboratory Press
2002
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC187484/ https://ncbi.nlm.nih.gov/pubmed/12435627 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1017302 |
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