A direct requirement for Hedgehog signaling for normal specification of all ventral progenitor domains in the presumptive mammalian spinal cord

The hedgehog signaling pathway organizes the developing ventral neural tube by establishing distinct neural progenitor fates along the dorsoventral axis. Smoothened (Smo) is essential for all Hedgehog (Hh) signaling, and genetic inactivation of Smo cells autonomously blocks the ability of cells to t...

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Detalhes bibliográficos

Publicado no:	Genes Dev
Principais autores:	Wijgerde, Mark, McMahon, Jill A., Rule, Michael, McMahon, Andrew P.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Cold Spring Harbor Laboratory Press 2002
Assuntos:	Research Paper
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC187482/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12435628/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1025702
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