A direct requirement for Hedgehog signaling for normal specification of all ventral progenitor domains in the presumptive mammalian spinal cord

The hedgehog signaling pathway organizes the developing ventral neural tube by establishing distinct neural progenitor fates along the dorsoventral axis. Smoothened (Smo) is essential for all Hedgehog (Hh) signaling, and genetic inactivation of Smo cells autonomously blocks the ability of cells to t...

Disgrifiad llawn

Manylion Llyfryddiaeth

Cyhoeddwyd yn:	Genes Dev
Prif Awduron:	Wijgerde, Mark, McMahon, Jill A., Rule, Michael, McMahon, Andrew P.
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	Cold Spring Harbor Laboratory Press 2002
Pynciau:	Research Paper
Mynediad Ar-lein:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC187482/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12435628/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1025702
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