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The pRb-related protein p130 is regulated by phosphorylation-dependent proteolysis via the protein–ubiquitin ligase SCF(Skp2)

p130 is a tumor suppressor of the pocket protein family whose expression is posttranscriptionally regulated and largely G0 restricted. The mechanism of down-regulation of p130 expression in proliferating cells was investigated. Our results indicate that the decline of p130 expression as G0 cells ree...

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Bibliografische gegevens
Gepubliceerd in:Genes Dev
Hoofdauteurs: Tedesco, Donato, Lukas, Jiri, Reed, Steven I.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cold Spring Harbor Laboratory Press 2002
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Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC187481/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12435635/
https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.1011202
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