Dorsal-ventral patterning of the spinal cord requires Gli3 transcriptional repressor activity

Sonic hedgehog (Shh) plays a critical role in organizing cell pattern in the developing spinal cord. Gli proteins are thought to mediate Shh signaling, but their role in directing neural tube patterning remains unclear. Here we identify a role for Gli3 transcriptional repressor activity in patternin...

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Detalhes bibliográficos
Main Authors: Persson, Madelen, Stamataki, Despina, te Welscher, Pascal, Andersson, Elisabet, Böse, Jens, Rüther, Ulrich, Ericson, Johan, Briscoe, James
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2002
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC187477/
https://ncbi.nlm.nih.gov/pubmed/12435629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.243402
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