Promoter proximal splice sites enhance transcription

Reconstruction of a gene with its introns removed results in reduced levels of cytoplasmic mRNA. This is partly explained by introns promoting the export of mRNA through coupling splicing to nuclear export processes. However, we show here that splicing signals can have a direct role in enhancing gen...

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Библиографические подробности

Опубликовано в::	Genes Dev
Главные авторы:	Furger, Andre, Binnie, Justin M. O‘Sullivan, Alexandra, Lee, Barbara A., Proudfoot, Nick J.
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Cold Spring Harbor Laboratory Press 2002
Предметы:	Research Paper
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC187476/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12414732/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.983602
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