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Donor T-cell alloreactivity against host thymic epithelium limits T-cell development after bone marrow transplantation
Acute graft-versus-host disease (aGVHD) impairs thymus-dependent T-cell regeneration in recipients of allogeneic bone marrow transplants through yet to be defined mechanisms. Here, we demonstrate in mice that MHC-mismatched donor T cells home into the thymus of unconditioned recipients. There, activ...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society of Hematology
2007
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1874583/ https://ncbi.nlm.nih.gov/pubmed/17213290 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-07-034157 |
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