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MEK1/2 inhibitors sensitize Bcr/Abl(+) human leukemia cells to the dual Abl/Src inhibitor BMS-354/825
Interactions between MEK1/2 inhibitors and the dual Abl/Src kinase inhibitor dasatinib (BMS-354825) were examined in chronic myeloid leukemia (CML) cell lines and primary specimens. Cotreatment of K562 or LAMA cells with subtoxic or marginally toxic concentrations of PD184352 (or U0126) and dasatini...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society of Hematology
2007
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1874569/ https://ncbi.nlm.nih.gov/pubmed/17218385 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-09-045039 |
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