Targeting aurora kinases as therapy in multiple myeloma

The aurora kinases facilitate transit from G2 through cytokinesis and, thus, are targets in cancer therapy. Multiple myeloma (MM) is a malignancy characterized by genetic instability, suggesting a disruption of checkpoints that arrest cells at G2M when injury to the mitotic machinery occurs. Since d...

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Bibliografische gegevens
Hoofdauteurs: Shi, Yijiang, Reiman, Tony, Li, Weiqun, Maxwell, Christopher A., Sen, Subrata, Pilarski, Linda, Daniels, Tracy R., Penichet, Manuel L., Feldman, Rick, Lichtenstein, Alan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society of Hematology 2007
Onderwerpen:
Neoplasia
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1874561/
https://ncbi.nlm.nih.gov/pubmed/17213289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-07-037671
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