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Targeting aurora kinases as therapy in multiple myeloma
The aurora kinases facilitate transit from G2 through cytokinesis and, thus, are targets in cancer therapy. Multiple myeloma (MM) is a malignancy characterized by genetic instability, suggesting a disruption of checkpoints that arrest cells at G2M when injury to the mitotic machinery occurs. Since d...
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| Autores principales: | , , , , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
American Society of Hematology
2007
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1874561/ https://ncbi.nlm.nih.gov/pubmed/17213289 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-07-037671 |
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