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Targeting aurora kinases as therapy in multiple myeloma
The aurora kinases facilitate transit from G2 through cytokinesis and, thus, are targets in cancer therapy. Multiple myeloma (MM) is a malignancy characterized by genetic instability, suggesting a disruption of checkpoints that arrest cells at G2M when injury to the mitotic machinery occurs. Since d...
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| Hlavní autoři: | , , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society of Hematology
2007
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1874561/ https://ncbi.nlm.nih.gov/pubmed/17213289 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-07-037671 |
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