Nur77 converts phenotype of Bcl-B, an antiapoptotic protein expressed in plasma cells and myeloma

Defects in apoptosis mechanisms play important roles in malignancy and autoimmunity. Orphan nuclear receptor Nur77/TR3 has been demonstrated to bind antiapoptotic protein Bcl-2 and convert it from a cytoprotective to a cytodestructive protein, representing a phenotypic conversion mechanism. Of the 6...

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Detalhes bibliográficos
Main Authors: Luciano, Frederic, Krajewska, Maryla, Ortiz-Rubio, Paulina, Krajewski, Stan, Zhai, Dayong, Faustin, Benjamin, Bruey, Jean-Marie, Bailly-Maitre, Beatrice, Lichtenstein, Alan, Kolluri, Siva Kumar, Satterthwait, Arnold C., Zhang, Xiao-Kun, Reed, John C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2007
Assuntos:
Immunobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1874560/
https://ncbi.nlm.nih.gov/pubmed/17227826
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2006-11-056879
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