Direct in vivo evidence of a vascular statin: a single dose of cerivastatin rapidly increases vascular endothelial responsiveness in healthy normocholesterolaemic subjects

AIMS: HMG-CoA reductase inhibitors (statins) have been demonstrated to have in vitro vascular effects. The aim of this study was to determine whether statins actually have in vivo vascular effects independent of their cholesterol-lowering effect. METHODS: We investigated the effect of a single dose...

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Main Authors: Omori, Hisako, Nagashima, Hirotaka, Tsurumi, Yukio, Takagi, Atsushi, Ishizuka, Naoko, Hagiwara, Nobuhisa, Kawana, Masatoshi, Kasanuki, Hiroshi
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 2002
Teme:
Pharmacodynamics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1874448/
https://ncbi.nlm.nih.gov/pubmed/12392587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2002.01677.x
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