Direct in vivo evidence of a vascular statin: a single dose of cerivastatin rapidly increases vascular endothelial responsiveness in healthy normocholesterolaemic subjects

AIMS: HMG-CoA reductase inhibitors (statins) have been demonstrated to have in vitro vascular effects. The aim of this study was to determine whether statins actually have in vivo vascular effects independent of their cholesterol-lowering effect. METHODS: We investigated the effect of a single dose...

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Detalhes bibliográficos
Main Authors: Omori, Hisako, Nagashima, Hirotaka, Tsurumi, Yukio, Takagi, Atsushi, Ishizuka, Naoko, Hagiwara, Nobuhisa, Kawana, Masatoshi, Kasanuki, Hiroshi
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2002
Assuntos:
Pharmacodynamics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1874448/
https://ncbi.nlm.nih.gov/pubmed/12392587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2002.01677.x
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