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Direct in vivo evidence of a vascular statin: a single dose of cerivastatin rapidly increases vascular endothelial responsiveness in healthy normocholesterolaemic subjects

AIMS: HMG-CoA reductase inhibitors (statins) have been demonstrated to have in vitro vascular effects. The aim of this study was to determine whether statins actually have in vivo vascular effects independent of their cholesterol-lowering effect. METHODS: We investigated the effect of a single dose...

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Bibliografiske detaljer
Main Authors: Omori, Hisako, Nagashima, Hirotaka, Tsurumi, Yukio, Takagi, Atsushi, Ishizuka, Naoko, Hagiwara, Nobuhisa, Kawana, Masatoshi, Kasanuki, Hiroshi
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Science Inc 2002
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1874448/
https://ncbi.nlm.nih.gov/pubmed/12392587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2002.01677.x
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