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Lack of pharmacokinetic interaction between the oral anti-influenza neuraminidase inhibitor prodrug oseltamivir and antacids

AIMS: Oseltamivir is an oral ester prodrug of its active metabolite Ro 64–0802, a potent and selective neuraminidase inhibitor of the influenza virus. The object of this study was to evaluate whether the oral absorption of oseltamivir was reduced in the presence of two main classes of antacid, Maalo...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Snell, Paul, Oo, Charles, Dorr, Al, Barrett, Joanne
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Inc 2002
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1874437/
https://ncbi.nlm.nih.gov/pubmed/12392584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2002.01678.x
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