Relationships between body composition parameters and fluorouracil pharmacokinetics

AIMS: To verify whether fluorouracil (FU) clearance (CL) and volume of distribution (V(ss)) are better correlated with specific body compartments, such as body cell mass (BCM), total body water (TBW) or fat free mass (FFM), rather than with body surface area (BSA) or total body weight (BW). METHODS:...

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Autors principals: Gusella, Milena, Toso, Sivia, Ferrazzi, Eros, Ferrari, Mariano, Padrini, Roberto
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Science Inc 2002
Matèries:
Pharmacokinetics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1874401/
https://ncbi.nlm.nih.gov/pubmed/12207632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2002.01598.x
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