Relationships between body composition parameters and fluorouracil pharmacokinetics

AIMS: To verify whether fluorouracil (FU) clearance (CL) and volume of distribution (V(ss)) are better correlated with specific body compartments, such as body cell mass (BCM), total body water (TBW) or fat free mass (FFM), rather than with body surface area (BSA) or total body weight (BW). METHODS:...

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Detalhes bibliográficos
Main Authors: Gusella, Milena, Toso, Sivia, Ferrazzi, Eros, Ferrari, Mariano, Padrini, Roberto
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2002
Assuntos:
Pharmacokinetics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1874401/
https://ncbi.nlm.nih.gov/pubmed/12207632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2002.01598.x
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