Pharmacokinetics and pharmacodynamics of combination chemotherapy with paclitaxel and epirubicin in breast cancer patients

AIMS: To investigate the pharmacokinetics and pharmacodynamics of epirubicin and paclitaxel in combination, as well as the effects of paclitaxel and its vehicle Cremophor EL on epirubicin metabolism. METHODS: Twenty-seven female patients with metastatic breast cancer received epirubicin 90 mg m(−2)...

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Detalhes bibliográficos
Main Authors: Danesi, Romano, Innocenti, Federico, Fogli, Stefano, Gennari, Alessandra, Baldini, Editta, Di Paolo, Antonello, Salvadori, Barbara, Bocci, Guido, Conte, Pier Franco, Del Tacca, Mario
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2002
Assuntos:
Pharmacokinetics/Pharmacodynamics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1874362/
https://ncbi.nlm.nih.gov/pubmed/11994057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2002.01579.x
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