The bioavailability and pharmacokinetics of subcutaneous, nebulized and oral morphine-6-glucuronide

AIMS: Morphine-6-glucuronide (M6G), one of the active metabolites of morphine, has attracted considerable interest as a potent opioid analgesic with an apparently superior therapeutic index. To date studies have used the intravenous route, which is generally unacceptable in the treatment of cancer r...

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Dettagli Bibliografici
Autori principali: Penson, Richard T, Joel, Simon P, Roberts, Michael, Gloyne, Anna, Beckwith, Stephen, Slevin, Maurice L
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2002
Soggetti:
Pharmacokinetics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1874271/
https://ncbi.nlm.nih.gov/pubmed/11966664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2002.01554.x
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