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A null mutation in the photoreceptor guanylate cyclase gene causes the retinal degeneration chicken phenotype

The retinas of the retinal degeneration (rd) chicken are fully developed and possess normal morphology at hatching but fail to respond to light stimulation. Analyses of retinal cGMP, the internal messenger of phototransduction, show that the amount of cGMP in predegenerate, fully developed rd/rd pho...

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Bibliografiska uppgifter
Huvudupphovsmän: Semple-Rowland, Susan L., Lee, Nancy R., Van Hooser, J. Preston, Palczewski, Krzysztof, Baehr, Wolfgang
Materialtyp: Artigo
Språk:Inglês
Publicerad: The National Academy of Sciences 1998
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC18742/
https://ncbi.nlm.nih.gov/pubmed/9448321
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