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An approach for dose finding of drugs in infants: sedation by midazolam studied using the continual reassessment method

AIMS: No drug has been demonstrated to provide simultaneously appropriate sedation, safety and lack of disturbance of the measured parameters during cardiac catheterization in infants. The objective of this study was to estimate the dose of midazolam, administered rectally, that would provide a 90%...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Fabre, Emmanuelle, Chevret, Sylvie, Piechaud, Jean-François, Rey, Elisabeth, Vauzelle-Kervroedan, Françoise, D’Athis, Phillippe, Olive, Georges, Pons, Gérard
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Science Ltd 1998
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1874155/
https://ncbi.nlm.nih.gov/pubmed/9803989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1998.00788.x
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