Variability at Human Immunodeficiency Virus Type 1 Subtype C Protease Cleavage Sites: an Indication of Viral Fitness?

Naturally occurring polymorphisms in the protease of human immunodeficiency virus type 1 (HIV-1) subtype C would be expected to lead to adaptive (compensatory) changes in protease cleavage sites. To test this hypothesis, we examined the prevalences and patterns of cleavage site polymorphisms in the...

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Vydáno v:	J Virol
Hlavní autoři:	de Oliveira, Tulio, Engelbrecht, Susan, Janse van Rensburg, Estrelita, Gordon, Michelle, Bishop, Karen, zur Megede, Jan, Barnett, Susan W., Cassol, Sharon
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 2003
Témata:	Recombination and Evolution
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC187406/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12915557/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.17.9422-9430.2003
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