Variability at Human Immunodeficiency Virus Type 1 Subtype C Protease Cleavage Sites: an Indication of Viral Fitness?

Naturally occurring polymorphisms in the protease of human immunodeficiency virus type 1 (HIV-1) subtype C would be expected to lead to adaptive (compensatory) changes in protease cleavage sites. To test this hypothesis, we examined the prevalences and patterns of cleavage site polymorphisms in the...

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Main Authors: de Oliveira, Tulio, Engelbrecht, Susan, Janse van Rensburg, Estrelita, Gordon, Michelle, Bishop, Karen, zur Megede, Jan, Barnett, Susan W., Cassol, Sharon
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2003
Assuntos:
Recombination and Evolution
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC187406/
https://ncbi.nlm.nih.gov/pubmed/12915557
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.17.9422-9430.2003
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