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Existence of Transdominant and Potentiating Mutants of UL9, the Herpes Simplex Virus Type 1 Origin-Binding Protein, Suggests that Levels of UL9 Protein May Be Regulated during Infection

UL9 is a multifunctional protein required for herpes simplex virus type 1 (HSV-1) replication in vivo. UL9 is a member of the superfamily II helicases and exhibits helicase and origin-binding activities. We have previously shown that mutations in the conserved helicase motifs of UL9 can have either...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Marintcheva, Boriana, Weller, Sandra K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC187383/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12915576/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.17.9639-9651.2003
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