Relationship between proguanil metabolic ratio and CYP2C19 genotype in a Caucasian population

AIMS: To investigate the relationship between proguanil metabolic ratio (MR, proguanil/cycloguanil) and CYP2C19 genotype in a Caucasian population. METHODS: Ninety-nine Caucasians (age range: 18–55 years, 54 female, 45 male) were genotyped for CYP2C19 and phenotyped for proguanil oxidation by collec...

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Detaylı Bibliyografya
Asıl Yazarlar: Hoskins, Janelle M, Shenfield, Gillian M, Gross, Annette S
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Blackwell Science Inc 1998
Konular:
Original Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1873690/
https://ncbi.nlm.nih.gov/pubmed/9833604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1998.00807.x
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