The absolute bioavailability and effect of food on the pharmacokinetics of zolmitriptan in healthy volunteers

AIMS: Zolmitriptan (Zomig (formerly 311C90)) is a novel 5-HT(1B/1D) receptor agonist developed for the acute oral treatment of migraine. A highly sensitive LCMS-MS assay has been developed which allows quantification of plasma concentrations of zolmitriptan and its active metabolite, 183C91, after t...

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Главные авторы: Seaber, Emma J, Peck, Richard W, Smith, Deborah A, Allanson, John, Hefting, Nanco R, van Lier, Jan J, Sollie, Frans A E, Wemer, Johan, Jonkman, Jan H G
Формат: Artigo
Язык:Inglês
Опубликовано: Blackwell Science Inc 1998
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Original Articles
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1873688/
https://ncbi.nlm.nih.gov/pubmed/9833595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.1998.00809.x
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