Ecteinascidin 743, a transcription-targeted chemotherapeutic that inhibits MDR1 activation

Ecteinascidin 743 (ET-743), a highly promising marine-based antitumor agent presently in phase II clinical trials, has been shown to interfere with the binding of minor-groove-interacting transcription factors, particularly NF-Y, with their cognate promoter elements in vitro. We have shown that NF-Y...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Jin, Shengkan, Gorfajn, Barbara, Faircloth, Glynn, Scotto, Kathleen W.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2000
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC18735/
https://ncbi.nlm.nih.gov/pubmed/10841572
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker