Both the Fas Ligand and Inducible Nitric Oxide Synthase Are Needed for Control of Parasite Replication within Lesions in Mice Infected with Leishmania major whereas the Contribution of Tumor Necrosis Factor Is Minimal

Following infection with the protozoan parasite Leishmania major, C57BL/6 mice develop a small lesion that heals spontaneously. Resistance to infection is associated with the development of CD4(+) Th1 cells producing gamma interferon (IFN-γ) and tumor necrosis factor (TNF), which synergize in activa...

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Bibliografiske detaljer
Main Authors: Chakour, Reza, Guler, Reto, Bugnon, Mélanie, Allenbach, Cindy, Garcia, Irène, Mauël, Jacques, Louis, Jacques, Tacchini-Cottier, Fabienne
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2003
Fag:
Fungal and Parasitic Infections
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC187307/
https://ncbi.nlm.nih.gov/pubmed/12933876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.71.9.5287-5295.2003
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