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Polynuclear platinum anticancer drugs are more potent than cisplatin and induce cell cycle arrest in glioma
We have evaluated the efficacy of the multinuclear platinum chemotherapeutics BBR3464, BBR3571, and BBR3610 against glioma cells in culture and animal models and investigated their mechanism of action at the cellular level. In a clonogenic assay, BBR3610, the most potent compound, had an IC(90) dose...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Duke University Press
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1871949/ https://ncbi.nlm.nih.gov/pubmed/16723633 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1215/15228517-2006-004 |
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