Constitutive integrin activation on tumor cells contributes to progression of leptomeningeal metastases

Leptomeningeal metastases are a serious neurological complication in cancer patients and associated with a dismal prognosis. Tumor cells that enter the subarachnoid space adhere to the leptomeninges and form tumor deposits. It is largely unknown which adhesion molecules mediate tumor cell adhesion t...

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Detalhes bibliográficos
Main Authors: Brandsma, Dieta, Ulfman, Laurien, Reijneveld, Jaap C., Bracke, Madelon, Taphoorn, Martin J.B., Zwaginga, Jaap Jan, Gebbink, Martijn F.B., de Boer, Hetty, Koenderman, Leo, Voest, Emile E.
Formato: Artigo
Idioma:Inglês
Publicado em: Duke University Press 2006
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1871936/
https://ncbi.nlm.nih.gov/pubmed/16533879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1215/15228517-2005-013
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