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In vivo selection for metastasis promoting genes in the mouse

Here, we report the identification of a metastasis promoting factor by a forward genetic screen in mice. A retroviral cDNA library was introduced into the nonmetastatic cancer cell line 168FARN, which was then orthotopically transplanted into mouse mammary fat pads, followed by selection for cells t...

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Bibliografiske detaljer
Main Authors: Gumireddy, Kiranmai, Sun, Fangxian, Klein-Szanto, Andres J., Gibbins, Jonathan M., Gimotty, Phyllis A., Saunders, Aleister J., Schultz, Peter G., Huang, Qihong
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2007
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1871848/
https://ncbi.nlm.nih.gov/pubmed/17420453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0701145104
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