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In vivo selection for metastasis promoting genes in the mouse
Here, we report the identification of a metastasis promoting factor by a forward genetic screen in mice. A retroviral cDNA library was introduced into the nonmetastatic cancer cell line 168FARN, which was then orthotopically transplanted into mouse mammary fat pads, followed by selection for cells t...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1871848/ https://ncbi.nlm.nih.gov/pubmed/17420453 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0701145104 |
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