Hematopoietic stem cell deficiencies in mice lacking c-Mpl, the receptor for thrombopoietin

Thrombopoietin (TPO) acts as a lineage-specific late-acting factor to stimulate megakaryocyte and platelet formation. However, analysis of mice lacking either the cytokine or its receptor, c-Mpl, also revealed deficiencies in progenitor cells of multiple hematopoietic lineages, suggesting that TPO s...

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Εκδόθηκε σε:	Proc Natl Acad Sci U S A
Κύριοι συγγραφείς:	Kimura, Shinya, Roberts, Andrew W., Metcalf, Donald, Alexander, Warren S.
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	National Academy of Sciences 1998
Θέματα:	Biological Sciences
Διαθέσιμο Online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18717/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9448308/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.3.1195
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