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In vivo efficacy of a novel histone deacetylase inhibitor in combination with radiation for the treatment of gliomas

Histone modification has emerged as a promising approach to cancer therapy. We explored the in vivo efficacy of a butyric acid derivative, pivaloyloxymethyl butyrate (AN-9), for the treatment of gliomas. Relative to control and single-modality treatments, the combination of AN-9 and radiation signif...

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Hlavní autoři: Entin-Meer, Michal, Yang, Xiaodong, VandenBerg, Scott R., Lamborn, Kathleen R., Nudelman, Abraham, Rephaeli, Ada, Haas-Kogan, Daphne Adele
Médium: Artigo
Jazyk:Inglês
Vydáno: Duke University Press 2007
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1871664/
https://ncbi.nlm.nih.gov/pubmed/17347490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1215/15228517-2006-032
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