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Metabolism of Deoxycorticosterone by Human Fecal Flora
21-Dehydroxylation, a feature of metabolism of corticoids in humans, was observed in mixed cultures of fecal flora of normal individuals on a Western diet. The model substrate, 11-deoxycorticosterone (DOC), was metabolized to 3α-21-dihydroxy-5β-pregnan-20-one (THDOC), 3α-hydroxy-5β-pregnan-20-one (p...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1975
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC187119/ https://ncbi.nlm.nih.gov/pubmed/238472 |
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