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Metabolism of Deoxycorticosterone by Human Fecal Flora

21-Dehydroxylation, a feature of metabolism of corticoids in humans, was observed in mixed cultures of fecal flora of normal individuals on a Western diet. The model substrate, 11-deoxycorticosterone (DOC), was metabolized to 3α-21-dihydroxy-5β-pregnan-20-one (THDOC), 3α-hydroxy-5β-pregnan-20-one (p...

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Detalhes bibliográficos
Publicado no:Appl Microbiol
Principais autores: Bokkenheuser, Victor D., Suzuki, Jon B., Polovsky, Stuart B., Winter, Jeanette, Kelly, William G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1975
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Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC187119/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/238472/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/am.30.1.82-90.1975
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