Metabolism of Deoxycorticosterone by Human Fecal Flora

21-Dehydroxylation, a feature of metabolism of corticoids in humans, was observed in mixed cultures of fecal flora of normal individuals on a Western diet. The model substrate, 11-deoxycorticosterone (DOC), was metabolized to 3α-21-dihydroxy-5β-pregnan-20-one (THDOC), 3α-hydroxy-5β-pregnan-20-one (p...

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Bibliografske podrobnosti
Main Authors: Bokkenheuser, Victor D., Suzuki, Jon B., Polovsky, Stuart B., Winter, Jeanette, Kelly, William G.
Format: Artigo
Jezik:Inglês
Izdano: 1975
Teme:
Metabolism and Products
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC187119/
https://ncbi.nlm.nih.gov/pubmed/238472
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