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Onset and progression of pathological lesions in transforming growth factor-beta 1-deficient mice.

Null-mutant (knockout) mice were obtained through disruption of the sixth exon of the endogenous transforming growth factor-beta 1 allele in murine embryonic stem cells via homologous recombination. Mice lacking transforming growth factor-beta 1 (mutants) were born grossly indistinguishable from wil...

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Détails bibliographiques
Auteurs principaux: Boivin, G. P., O'Toole, B. A., Orsmby, I. E., Diebold, R. J., Eis, M. J., Doetschman, T., Kier, A. B.
Format: Artigo
Langue:Inglês
Publié: 1995
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1870775/
https://ncbi.nlm.nih.gov/pubmed/7856734
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