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A fusion DNA vaccine that targets antigen-presenting cells increases protection from viral challenge

Improving the immunological potency, particularly the Ab response, is a serious hurdle for the protective efficacy and hence broad application of DNA vaccines. We examined the immunogenicity and protective efficacy of a hemagglutinin-based influenza DNA vaccine that was targeted to antigen-presentin...

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Detalhes bibliográficos
Main Authors: Deliyannis, Georgia, Boyle, Jefferey S., Brady, Jamie L., Brown, Lorena E., Lew, Andrew M.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC18699/
https://ncbi.nlm.nih.gov/pubmed/10823919
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