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Structure-function analysis of integrase interactor 1/hSNF5L1 reveals differential properties of two repeat motifs present in the highly conserved region

Retroviral integrase (IN) catalyzes the integration of retroviral cDNA into host chromosome. Ini1 (integrase interactor 1) is a host protein that specifically binds and stimulates in vitro joining activity of HIV-1 IN. Ini1 has homology to yeast transcription factor SNF5 and is a component of the an...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Morozov, Alexei, Yung, Eric, Kalpana, Ganjam V.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1998
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC18693/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9448295/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.3.1120
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