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A global proteomics approach identifies novel phosphorylated signaling proteins in GPVI-activated platelets: involvement of G6f, a novel platelet Grb2-binding membrane adapter

Collagen-related peptide (CRP) stimulates powerful activation of platelets through the GPVI-FcR γ-chain complex. We have combined proteomics and traditional biochemistry approaches to study the proteome of CRP-activated platelets, focusing in detail on tyrosine phosphorylation. In two separate appro...

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Detalhes bibliográficos
Main Authors: García, Ángel, Senis, Yotis A., Antrobus, Robin, Hughes, Craig E., Dwek, Raymond A., Watson, Steve P., Zitzmann, Nicole
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1869047/
https://ncbi.nlm.nih.gov/pubmed/16941570
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pmic.200600299
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