A case for “StopGo”: Reprogramming translation to augment codon meaning of GGN by promoting unconventional termination (Stop) after addition of glycine and then allowing continued translation (Go)

When a eukaryotic mRNA sequence specifying an amino acid motif known as 2A is directly followed by a proline codon, two nonoverlapping proteins are synthesized. From earlier work, the second protein is known to start with this proline codon and is not created by proteolysis. Here we identify the C-t...

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Detalhes bibliográficos
Main Authors: Atkins, John F., Wills, Norma M., Loughran, Gary, Wu, Chih-Yu, Parsawar, Krishna, Ryan, Martin D., Wang, Chung-Hsiung, Nelson, Chad C.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2007
Assuntos:
Letter to the Editor
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1869043/
https://ncbi.nlm.nih.gov/pubmed/17456564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.487907
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