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Structural features of the guide:target RNA duplex required for archaeal box C/D sRNA-guided nucleotide 2′-O-methylation

Archaeal box C/D sRNAs guide the 2′-O-methylation of target nucleotides using both terminal box C/D and internal C′/D′ RNP complexes. In vitro assembly of a catalytically active Methanocaldococcus jannaschii sR8 box C/D RNP provides a model complex to determine those structural features of the guide...

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Autors principals: Appel, C. Denise, Maxwell, E. Stuart
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1869030/
https://ncbi.nlm.nih.gov/pubmed/17438123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.517307
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