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Efficient RNA 2′-O-methylation requires juxtaposed and symmetrically assembled archaeal box C/D and C′/D′ RNPs
Box C/D ribonucleoprotein (RNP) complexes direct the nucleotide-specific 2′-O-methylation of ribonucleotide sugars in target RNAs. In vitro assembly of an archaeal box C/D sRNP using recombinant core proteins L7, Nop56/58 and fibrillarin has yielded an RNA:protein enzyme that guides methylation from...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC169041/ https://ncbi.nlm.nih.gov/pubmed/12881427 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdg368 |
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