Affinity maturation of immunoglobulin A anti-tissue transglutaminase autoantibodies during development of coeliac disease

Coeliac disease (CD) is an immune-mediated enteropathy triggered by ingestion of wheat gluten and related cereals in genetically predisposed individuals. Circulating immunoglobulin A (IgA) class autoantibodies against tissue transglutaminase (IgA–TGA) are highly specific and sensitive serological ma...

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Autori principali: Westerlund, A, Ankelo, M, Simell, S, Ilonen, J, Knip, M, Simell, O, Hinkkanen, A E
Natura: Artigo
Lingua:Inglês
Pubblicazione: Blackwell Science Inc 2007
Soggetti:
Translational Studies
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868886/
https://ncbi.nlm.nih.gov/pubmed/17286799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2249.2007.03336.x
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