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A proline repeat domain in the Notch co-activator MAML1 is important for the p300-mediated acetylation of MAML1
Ligand activation of Notch leads to the release of Notch IC (the intracellular receptor domain), which translocates to the nucleus and interacts with the DNA-binding protein CSL to control expression of specific target genes. In addition to ligand-mediated activation, Notch signalling can be further...
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Main Authors: | , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Portland Press Ltd.
2007
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1868802/ https://ncbi.nlm.nih.gov/pubmed/17300219 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20061900 |
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