Prolonged expression of a lysosomal enzyme in mouse liver after Sleeping Beauty transposon-mediated gene delivery: implications for non-viral gene therapy of mucopolysaccharidoses

BACKGROUND: The Sleeping Beauty (SB) transposon system is a non-viral vector system that can integrate precise sequences into chromosomes. We evaluated the SB transposon system as a tool for gene therapy of mucopolysaccharidosis (MPS) types I and VII. METHODS: We constructed SB transposon plasmids f...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Aronovich, Elena L., Bell, Jason B., Belur, Lalitha R., Gunther, Roland, Koniar, Brenda, Erickson, David C. C., Schachern, Patricia A., Matise, Ilze, McIvor, R. Scott, Whitley, Chester B., Hackett, Perry B.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2007
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868578/
https://ncbi.nlm.nih.gov/pubmed/17407189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jgm.1028
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items