Human progenitor cells rapidly mobilized by AMD3100 repopulate NOD/SCID mice with increased frequency in comparison to cells from the same donor mobilized by granulocyte colony stimulating factor

AMD3100 inhibits the interaction between SDF-1 and CXCR4, and rapidly mobilizes hematopoietic progenitors for clinical transplantation. However, the repopulating function of human cells mobilized with AMD3100 has not been characterized in comparison to cells mobilized with G-CSF in the same donor. T...

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Hauptverfasser: Hess, David A., Bonde, Jesper, Craft, Timothy C., Wirthlin, Louisa, Hohm, Sarah, Lahey, Ryan, Todt, Laura M., Dipersio, John F., Devine, Steven M., Nolta, Jan A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2007
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868544/
https://ncbi.nlm.nih.gov/pubmed/17382247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2006.12.445
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