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The MTHFR 677TT genotype and folate intake interact to lower global leukocyte DNA methylation in young Mexican American women.

DNA methylation is an epigenetic feature that is associated with X chromosome inactivation, genomic imprinting, transcriptional silencing of genes and genomic stability. Folate provides a labile source of methyl groups which may be used for cellular methylation reactions including DNA methylation. T...

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Main Authors: Axume, Juan, Smith, Steven S, Pogribny, Igor P, Moriarty, David J., Caudill., Marie A.
Formato: Artigo
Idioma:Inglês
Publicado: 2007
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1868448/
https://ncbi.nlm.nih.gov/pubmed/18167510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nutres.2006.12.006
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