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The MTHFR 677TT genotype and folate intake interact to lower global leukocyte DNA methylation in young Mexican American women.
DNA methylation is an epigenetic feature that is associated with X chromosome inactivation, genomic imprinting, transcriptional silencing of genes and genomic stability. Folate provides a labile source of methyl groups which may be used for cellular methylation reactions including DNA methylation. T...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2007
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1868448/ https://ncbi.nlm.nih.gov/pubmed/18167510 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nutres.2006.12.006 |
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